Post‐diagnosis physical activity and sedentary behaviour and colorectal cancer prognosis: A Global Cancer Update Programme (CUP Global) systematic literature review and meta‐analysis | Semantic Scholar (2024)

There was evidence of non‐linearity in the associations between body mass index and colorectal cancer prognosis and well‐designed intervention and cohort studies are needed to support the development of lifestyle recommendations for colorectal cancer patients.

A systematic review and meta‐analysis on post‐diagnosis adiposity measures (body mass index, waist circumference, waist‐to‐hip ratio, weight) or their changes and colorectal cancer outcomes indicated a reverse J‐shaped association between BMI and colorectal cancer outcomes.

Additional, well‐conducted cohort studies and carefully designed RCTs are needed to develop specific lifestyle recommendations for colorectal cancer survivors.

There was evidence of non‐linearity in the associations between body mass index and colorectal cancer prognosis and well‐designed intervention and cohort studies are needed to support the development of lifestyle recommendations for colorectal cancer patients.

A systematic review and meta‐analysis on post‐diagnosis adiposity measures (body mass index, waist circumference, waist‐to‐hip ratio, weight) or their changes and colorectal cancer outcomes indicated a reverse J‐shaped association between BMI and colorectal cancer outcomes.

Additional, well‐conducted cohort studies and carefully designed RCTs are needed to develop specific lifestyle recommendations for colorectal cancer survivors.

Physical activity performed before or after cancer diagnosis is related to reduced mortality risk among breast and colorectal cancer survivors.

Recreational physical activity after the diagnosis of stages I to III colorectal cancer may reduce the risk of coloreCTal cancer-specific and overall mortality.

In a large cohort of men with a history of nonmetastatic colorectal cancer, more physical activity was associated with a lower risk of coloreCTal cancer-specific and overall mortality.

Investigation of the association of lifetime and latest prediagnostic leisure time physical activity with relevant prognostic outcomes in a large population‐based cohort of CRC patients found Prediagnostics physical activity was associated with improved CRC prognosis.

The findings suggest that higher physical activity around the time of colon cancer diagnosis may be associated with more favorable colon cancer outcomes, and support further research on whether colon cancer survival may be enhanced by physical activity.

Increased central adiposity and a lack of regular physical activity prior to the diagnosis of colorectal cancer is associated with poorer overall and disease specific survival.

Increased physical activity was associated with improved quality of life, a reduced risk of colorectal cancer, and overall mortality rate, and this finding should be interpreted with caution.

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